Steroid-resistant nephrotic syndrome: a persistent challenge for pediatric nephrology

被引：0
作者：
Samriti Dogra
Frederick Kaskel
机构：
[1] Connecticut Children’s Medical Center,Division of Pediatric Nephrology, Department of Pediatrics
[2] Albert Einstein College of Medicine,Division of Pediatric Nephrology, Department of Pediatrics, Children’s Hospital at Montefiore Medical Center
来源：
Pediatric Nephrology | 2017年 / 32卷
关键词：
Steroid-resistant nephrotic syndrome; Focal segmental glomerulosclerosis; Minimal change disease; Genetic testing; Glomerular filtration barrier; Podocyte;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Steroid-resistant nephrotic syndrome remains a challenge to treat, but various efforts are underway to better understand the pathogenesis and improve patient outcomes. This review provides an update on the newer advances in understanding the molecular etiologies for a variety of podocyte abnormalities, potential circulating factors that may initiate and sustain the steroid-resistant state, genetic mutations, and precision medicine treatment modalities in this continuously perplexing disorder.
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页码：965 / 974
页数：9
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