Transfer of the IL-37b gene elicits anti-tumor responses in mice bearing 4T1 breast cancer

被引:0
作者
Wei-qiang Wang
Dan Zhao
Yu-shan Zhou
Xiao-yu Hu
Zhi-na Sun
Gang Yu
Wan-tong Wu
Song Chen
Jiu-long Kuang
Guo-gang Xu
Zhong-chao Han
Bang-mao Wang
Jing-xian Yang
Xiao-ming Feng
机构
[1] State Key Laboratory of Experimental Hematology,Department of Gastroenterology and Hepatology
[2] Institute of Hematology and Hospital of Blood Disease,Department of Respiratory Medicine
[3] Chinese Academy of Medical Sciences,Nanlou Department of Pulmonary Medicine
[4] General Hospital,undefined
[5] Tianjin Medical University,undefined
[6] College of Pharmacy,undefined
[7] Liaoning University of Traditional Chinese Medicine,undefined
[8] the Second Affiliated Hospital of Nanchang University,undefined
[9] Beijing 301 Hospital,undefined
来源
Acta Pharmacologica Sinica | 2015年 / 36卷
关键词
IL-37b; breast cancer; anti-cancer effect; mitomycin C; T cell; tumor microenvironment;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:528 / 534
页数:6
相关论文
共 139 条
  • [1] Boraschi D(2011)IL-37: a new anti-inflammatory cytokine of the IL-1 family Eur Cytokine Netw 22 127-47
  • [2] Lucchesi D(2014)Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses Proc Natl Acad Sci U S A 111 2650-5
  • [3] Hainzl S(2010)IL-37 is a fundamental inhibitor of innate immunity Nat Immunol 11 1014-22
  • [4] Leitner M(2011)Interleukin 37 expression protects mice from colitis Proc Natl Acad Sci U S A 108 16711-6
  • [5] Maier E(2004)Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity FEBS Lett 577 93-100
  • [6] Mangelberger D(2003)Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity J immunol 170 107-13
  • [7] Bulau AM(2014)Interleukin-37 mediates the antitumor activity in hepatocellular carcinoma: role for CD57 Sci Rep 4 5177-72
  • [8] Nold MF(1999) NK cells Hum Gene Ther 10 2667-9
  • [9] Li S(2000)A high-efficiency Cre/loxP-based system for construction of adenoviral vectors Hum Gene Ther 11 693-14
  • [10] Nold-Petry CA(2013)An enhanced system for construction of adenoviral vectors by the two-plasmid rescue method PloS One 8 e74753-7