Unique characteristics of bat rabies viruses in big brown bats (Eptesicus fuscus)

被引：0
作者：
April D. Davis
Paul A. Gordy
Richard A. Bowen
机构：
[1] Colorado State University,Department of Microbiology, Immunology and Pathology
[2] Wadsworth Center,Rabies Laboratory, New York State Department of Health
[3] Colorado State University,Department of Biomedical Sciences
来源：
Archives of Virology | 2013年 / 158卷
关键词：
Salivary Gland; Rabies; Rabies Virus; Oral Swab; Rabies Virus Infection;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Rabies virus infection has been documented in several North American bat species, including Eptesicus fuscus. The virus-host relationship between bats and rabies virus (RV) is not well understood. The incidence of non-lethal RV exposure, based on the presence of viral neutralizing antibodies, demonstrates that exposure to RV does not always lead to clinical infection in bats. It is unknown how the route of exposure, rabies virus variant, or health of the bat affects the outcome following exposure. This paper describes the pathogenesis of two big brown bat RV variants in homologous host species. Our study demonstrates that RV variants obtained from the same species of bat from similar geographical areas may result in a diverse clinical progression of disease.
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页码：809 / 820
页数：11
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