Influence of Age on Baroreflex Synchronization of Blood Pressure and Heart Rate during the Passive Tilt Test

被引：0
作者：
Orlova E.A. [1 ]
Tarasova O.S. [1 ,2 ]
Son’kin V.D. [3 ]
Borovik A.S. [1 ]
机构：
[1] Institute of Biomedical Problems, Russian Academy of Sciences, Moscow
[2] Moscow State University, Moscow
[3] Institute of Developmental Physiology, Russian Academy of Education, Moscow
来源：
Human Physiology | 2022年 / 48卷 / 7期
基金：
俄罗斯基础研究基金会;
关键词：
age-related changes; AP; head-up tilt test; HR; phase synchronization index;
D O I：
10.1134/S0362119722070088
中图分类号：
学科分类号：
摘要：
Abstract: Age-related changes in phase synchronization of spontaneous mean arterial pressure (MAP) and heart rate (HR) fluctuations within the baroreflex wave range (around 0.1 Hz) were studied in 66 subjects aged 20 to 52 years. During the head-up tilt test, MAP (photocompensation method), ECG (to calculate heart rate), and respiratory rate were continuously recorded. To quantify MAP–HR coupling, the phase synchronization index (PSI) was used. In people over 40 years, an increase in phase synchronization of MAP and HR was found in a supine position compared with subjects aged 20–24 years. At the same time, the increase in PSI of MAP and HR in response to orthostatic stress decreased after the age of 40, which may reflect a decrease in baroreflex activity with age. © 2022, Pleiades Publishing, Inc.
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页码：822 / 826
页数：4
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