L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles

被引:0
作者
Fabio Fusi
Simona Saponara
Maria Frosini
Beatrice Gorelli
Giampietro Sgaragli
机构
[1] Università degli Studi di Siena,Dipartimento di Scienze Anatomiche e Biomediche
来源
Naunyn-Schmiedeberg's Archives of Pharmacology | 2003年 / 368卷
关键词
(S)-(-)-Bay K 8644; Myricetin; Vascular smooth muscle; Whole-cell patch-clamp; Wine polyphenols;
D O I
暂无
中图分类号
学科分类号
摘要
The effects of myricetin (3,3’,4’,5,5’,7-hesahydroxyflavone), a natural flavonoid found in edible plants, were studied on vascular smooth muscle L-type Ca2+ channels by comparing its mechanical, radioligand binding, and electrophysiological properties to those of the Ca2+ channel agonist (S)-(-)-Bay K 8644.
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页码:470 / 478
页数:8
相关论文
共 23 条
  • [1] Berger undefined(1992)undefined J Pharmacol Exp Ther 263 78-undefined
  • [2] Bradford undefined(1976)undefined Anal Biochem 72 248-undefined
  • [3] Cheng undefined(1973)undefined Biochem Pharmacol 22 3099-undefined
  • [4] Duarte undefined(1993)undefined Eur J Pharmacol 239 1-undefined
  • [5] Erlund undefined(2000)undefined Eur J Clin Pharmacol 56 545-undefined
  • [6] Fusi undefined(2000)undefined Eur J Pharmacol 394 109-undefined
  • [7] Fusi undefined(2001)undefined Br J Pharmacol 133 988-undefined
  • [8] Fusi undefined(2003)undefined Eur J Nutr 42 10-undefined
  • [9] Graefe undefined(2001)undefined J Clin Pharmacol 41 492-undefined
  • [10] Hamill undefined(1981)undefined Pflugers Arch 391 85-undefined