Depression and Viral Suppression Among Adults Living with HIV in Tanzania

被引：0
作者：
Mathilda Regan
Alfa Muhihi
Tumaini Nagu
Said Aboud
Nzovu Ulenga
Sylvia Kaaya
Mary C. Smith Fawzi
Aisha K. Yousafzai
Ferdinand Mugusi
Wafaie W. Fawzi
Shekhar Saxena
Karestan Koenen
Christopher R. Sudfeld
机构：
[1] Harvard T H Chan School of Public Health,Department of Global Health and Population
[2] Management and Development for Health,Department of Internal Medicine
[3] Muhimbili University of Health and Allied Sciences,Department of Microbiology and Immunology
[4] Muhimbili University of Health and Allied Sciences,Department of Psychiatry and Mental Health
[5] Muhimbili University of Health and Allied Sciences,Department of Global Health and Social Medicine
[6] Harvard Medical School,Department of Epidemiology
[7] Harvard T H Chan School of Public Health,undefined
来源：
AIDS and Behavior | 2021年 / 25卷
关键词：
Depression; Viral suppression; Gender; Sub-Saharan Africa; Tanzania;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Limited information is available on the association between depression and viral suppression among people living with HIV (PLH) in sub-Saharan Africa. We conducted a prospective cohort study of 3996 adults initiating antiretroviral therapy (ART) in Dar es Salaam, Tanzania. Log-binomial models were used to assess the association between depression and the risk of an unsuppressed viral load (> 400 copies/mL) after 6 months of ART. Women who had depression at both initiation and after 6 months of treatment had 1.94 times (95% CI 1.22, 3.09; z = 2.78, p < 0.01) the risk of an unsuppressed viral load after 6 months of treatment as compared to women who did not have depression at either time point. Men with the top tertile of depressive symptoms after 6 months of treatment had 1.58 times the risk of an unsuppressed viral load (95% CI 1.04, 2.38; z = 2.15, p = 0.03) as compared to the lowest tertile. Research should be pursued on interventions to prevent and address depression among adults initiating ART to potentially support achievement of viral suppression.
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页码：3097 / 3105
页数：8
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