Formation of bronchus-associated lymphoid tissue (BALT) for early life immune protection

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Nature Immunology | 2023年 / 24卷
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Susceptibility to respiratory pathogens is increased during early life, yet children can mount highly effective immune responses to novel pathogens in the absence of a fully developed immune system. We found that bronchus-associated lymphoid tissue (BALT) develops in the lungs early in life and supports germinal center formation and B cell differentiation to produce antibodies specific for respiratory pathogens, revealing a mechanism for immune protection in an as-yet-undeveloped immune system.
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页码：1228 / 1229
页数：1
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