The role of IL-1β in Pseudomonas aeruginosa in lung infection

被引：0
作者：
B. Wonnenberg
M. Bischoff
C. Beisswenger
T. Dinh
R. Bals
B. Singh
T. Tschernig
机构：
[1] Saarland University,Department of Anatomy and Cell Biology
[2] Saarland University,Institute of Medical Microbiology and Hygiene
[3] Saarland University,Department of Internal Medicine V, Pneumology, Allergology and Respiratory Critical Care Medicine
[4] Saarland University,Department of Experimental Pneumology and Allergology
[5] University of Saskatchewan,Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine
来源：
Cell and Tissue Research | 2016年 / 364卷
关键词：
Pneumonia; Inflammation; IL-1β; Inflammasomes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This mini-review examines the role of the pro-inflammatory cytokine interleukin (IL)-1β in the interaction of Pseudomonas aeruginosa and the host immune system during lung infection. Different studies show that the reduction of the inflammatory response, especially a decrease in IL-1β, leads to a better outcome in acute lung infection with this bacterium. This includes a higher survival rate, reduced damage to the lung tissue and, in particular, a better clearance of the airways and the tissue of the lungs from P. aeruginosa.
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页码：225 / 229
页数：4
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