Formation of multicellular aggregates under different conditions of microenvironment

被引：0
|
作者：
L. V. Garmanchuk
E. M. Perepelitsyna
M. V. Sydorenko
L. I. Ostapchenko
机构：
[1] Department of Biotecftntcal Problems of Diagnostics Institute Problems of Cryobiology and Criomedicine NAN Ukraine,
[2] Taras Shevchenko Kiev National University,undefined
来源：
Cytology and Genetics | 2010年 / 44卷
关键词：
Fetal Calf Serum; Tumor Spheroid; Spheroid Formation; Spinner Flask; Carboxy Methyl Cellulose;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Multicellular aggregates (spheroids) represent an intermittent level between monolayer growing cells and tissue culture. Spheroids are rather objective model of the three-dimensional growth and organization, the cell-to-cell interactions and influence of microenvironmental conditions on tumour microaggre-gates. In our work formation and growth of spheroids depends on concentration of CMC and FCS. Conditions of microenvironment influence on intensiveness of proliferation as well as on cells adhesiveness and formation of microaggregates.
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页码：19 / 22
页数：3
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