Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

被引:0
|
作者
Subra Kugathasan
Robert N Baldassano
Jonathan P Bradfield
Patrick M A Sleiman
Marcin Imielinski
Stephen L Guthery
Salvatore Cucchiara
Cecilia E Kim
Edward C Frackelton
Kiran Annaiah
Joseph T Glessner
Erin Santa
Tara Willson
Andrew W Eckert
Erin Bonkowski
Julie L Shaner
Ryan M Smith
F George Otieno
Nicholas Peterson
Debra J Abrams
Rosetta M Chiavacci
Robert Grundmeier
Petar Mamula
Gitit Tomer
David A Piccoli
Dimitri S Monos
Vito Annese
Lee A Denson
Struan F A Grant
Hakon Hakonarson
机构
[1] Children's Research Institute and Medical College of Wisconsin,Department of Pediatrics
[2] Emory University School of Medicine and Children's Health Care of Atlanta,Department of Pediatrics
[3] Abramson Research Center,Division of Gastroenterology
[4] The Children's Hospital of Philadelphia,Department of Pediatrics
[5] Abramson Research Center,Department of Pediatrics
[6] The Children's Hospital of Philadelphia,Division of Gastroenterology
[7] The Center for Applied Genomics,Department of Pediatrics
[8] Abramson Research Center,Divisions of Immunology
[9] The Children's Hospital of Philadelphia,Divisions of Pathology
[10] University of Utah School of Medicine and Primary Children's Medical Center,Division of Human Genetics
[11] Pediatric Gastroenterology and Liver Unit,undefined
[12] Sapienza University of Rome,undefined
[13] Cincinnati Children's Hospital Medical Center,undefined
[14] University of Pennsylvania School of Medicine,undefined
[15] Center for Biomedical Informatics,undefined
[16] The Children's Hospital of Philadelphia,undefined
[17] The Children's Hospital of Philadelphia,undefined
[18] The Children's Hospital of Philadelphia,undefined
[19] Units of Gastroenterology,undefined
[20] IRCCS,undefined
[21] “Casa Sollievo della Sofferenza” Hospital,undefined
[22] Units of Endoscopy,undefined
[23] IRCCS,undefined
[24] “Casa Sollievo della Sofferenza” Hospital,undefined
[25] The Children's Hospital of Philadelphia,undefined
来源
Nature Genetics | 2008年 / 40卷
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摘要
Hakon Hakonarson and colleagues report the identification of two new susceptibility loci for inflammatory bowel disease (IBD). One variant is near a gene encoding tumor necrosis factor receptor subfamily member 6B and is associated with increased levels of this protein in serum from individuals with IBD.
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页码:1211 / 1215
页数:4
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