Antihypoxic Activity of Native Humic Acids of Tomsk Lowland Peat

被引:0
作者
M. V. Belousov
R. R. Akhmedzhanov
M. V. Zykova
A. N. Arbuzov
A. M. Gur’ev
M. S. Yusubov
机构
[1] Siberian State Medical University,Research Institute of Cardiology, Siberian Branch
[2] Tomsk National Research Polytechnic University,undefined
[3] Russian Academy of Medical Sciences,undefined
来源
Pharmaceutical Chemistry Journal | 2014年 / 48卷
关键词
humic acids; antihypoxic activity; peat;
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学科分类号
摘要
The antihypoxic activity of humic acids of Tomsk lowland peat was studied experimentally. It was established that native humic acids of peat (HAP) had pronounced antihypoxic activity after a preventive intragastric administration to mice, increasing the lifespan of animals and decreasing the lethality under hypobaric hypoxic and histotoxic hypoxia conditions. The discovered antihypoxic properties of HAP were probably due to their protective antioxidant properties, which prevent free-radical injury to cells and organelles under hypoxia conditions.
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页码:97 / 99
页数:2
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