Paget's disease of bone—genetic and environmental factors

被引：0
作者：
Frederick R. Singer
机构：
[1] John Wayne Cancer Institute,
[2] Providence Saint Johns Health Center,undefined
来源：
Nature Reviews Endocrinology | 2015年 / 11卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The prevalence of Paget's disease has decreased in many countriesA large number of patients have a family history of Paget's diseaseMutations in SQSTM1 (which encodes sequestosome-1) account for the susceptibility to develop Paget's disease in some familiesSome studies in patients with Paget's disease and in transgenic mice support the involvement of measles virus in the aetiology of the disorderThe availability of effective measles vaccines since 1963 might explain the decrease in diagnosis of Paget's disease in a number of countries
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页码：662 / 671
页数：9
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