Bowels control brain: gut hormones and obesity

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作者
Benjamin C. T. Field
Owais B. Chaudhri
Stephen R. Bloom
机构
[1] Endocrinology and Metabolism,Division of Diabetes
[2] Imperial College London,undefined
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摘要
The gastrointestinal tract is an important source of endocrine signals. Gut hormones such as glucagon-like peptide 1, peptide YY, and islet amyloid polypeptide act in an integrated fashion to modulate appetite and energy expenditure. This Review addresses the physiological roles of gut hormones and discusses their potential as targets for the development of novel treatments for obesity, on the basis of pharmacological mimicry of the hormonal milieu after bariatric surgery.
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页码:444 / 453
页数:9
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