Quantitative comparison of technetium-99m tetrofosmin and thallium-201 images of the thyroid and abnormal parathyroid glands

被引:0
|
作者
Alessandro Giordano
Paola Marozzi
Guido Meduri
Umberto Ficola
Maria Lucia Calcagni
Angelo Vaccaro
Giuseppe Rubini
Marco Attard
Maria Li Puma
Riccardo Ricci
Salvatore Corsello
机构
[1] Catholic University of the Sacred Heart,
[2] Department of Nuclear Medicine,undefined
[3] Largo A. Gemelli 8,undefined
[4] I-00168 Roma,undefined
[5] Italy,undefined
[6] Department of Endocrinology,undefined
[7] Catholic University of the Sacred Heart,undefined
[8] Rome,undefined
[9] Italy,undefined
[10] Department of Nuclear Medicine,undefined
[11] Cervello Hospital,undefined
[12] Palermo,undefined
[13] Italy,undefined
[14] Department of Endocrinology,undefined
[15] Cervello Hospital,undefined
[16] Palermo,undefined
[17] Italy,undefined
[18] Department of Nuclear Medicine of the University,undefined
[19] Bari,undefined
[20] Italy,undefined
[21] Department of Pathology,undefined
[22] Catholic University of the Sacred Heart,undefined
[23] Rome,undefined
[24] Italy,undefined
来源
European Journal of Nuclear Medicine | 1999年 / 26卷
关键词
Key words: Technetium-99m tetrofosmin; Thallium-201; Parathyroid scintigraphy; Thyroid scintigraphy;
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摘要
The aim of the study was to quantitatively compare the scintigraphic images of the thyroid and abnormal parathyroid glands obtained with technetium-99m tetrofosmin and thallium-201 in patients with hyperparathyroidism. Forty-six patients with hyperparathyroidism underwent 201Tl (74 MBq), 99mTc-pertechnetate (74 MBq) and 99mTc-tetrofosmin (555–740 MBq) scintigraphy in a single session. Image analysis included the computation of the thyroid/background ratio in the whole study population and the parathyroid/background ratio, parathyroid/thyroid ratio and diagnostic sensitivity in 17 patients who underwent parathyroid surgery. The pertechnetate subtraction technique was used. 201Tl and 99mTc-tetrofosmin showed a similar thyroid/background ratio (1.79±0.41 and 1.81±0.47, respectively, P=NS); however, 99mTc-tetrofosmin showed a higher parathyroid/background ratio than 201Tl (2.06±0.54 vs 1.79± 0.50, P=0.007). Despite the superior quality of 99mTc-tetrofosmin images, both tracers showed identical sensitivity in detecting enlarged parathyroid glands in patients with primary hyperparathyroidism (89%) and in those with secondary hyperparathyroidism (50%).
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页码:907 / 911
页数:4
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