Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells

被引：0

作者：

Joana Carrelha

Yiran Meng

Laura M. Kettyle

Tiago C. Luis

Ruggiero Norfo

Verónica Alcolea

Hanane Boukarabila

Francesca Grasso

Adriana Gambardella

Amit Grover

Kari Högstrand

Allegra M. Lord

Alejandra Sanjuan-Pla

Petter S. Woll

Claus Nerlov

Sten Eirik W. Jacobsen

机构：

[1] Haematopoietic Stem Cell Laboratory,Radcliffe Department of Medicine

[2] MRC Weatherall Institute of Molecular Medicine,Radcliffe Department of Medicine

[3] University of Oxford,Department of Cell and Molecular Biology

[4] MRC Molecular Haematology Unit,Department of Medicine Huddinge

[5] MRC Weatherall Institute of Molecular Medicine,Division of Experimental Hematology and Cancer Biology

[6] University of Oxford,Hematology Research Group

[7] Wallenberg Institute for Regenerative Medicine,undefined

[8] Karolinska Institutet,undefined

[9] Karolinska Institutet,undefined

[10] Center for Hematology and Regenerative Medicine,undefined

[11] Karolinska Institutet,undefined

[12] Karolinska University Hospital,undefined

[13] Cincinnati Children's Hospital Medical Center and University of Cincinnati,undefined

[14] Instituto de Investigación Sanitaria La Fe,undefined

来源：

Nature | 2018年 / 554卷

关键词：

D O I：

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学科分类号：

摘要：

Analysis of transplantation of single haematopoietic stem cells in mice defines stable lineage-restricted fates in long-term self-renewing multipotent stem cells, including a class of multipotent stem cells that exclusively replenishes the megakaryocyte/platelet lineage.

引用

页码：106 / 111

页数：5

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