Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells

被引：0
|
作者：
Joana Carrelha
Yiran Meng
Laura M. Kettyle
Tiago C. Luis
Ruggiero Norfo
Verónica Alcolea
Hanane Boukarabila
Francesca Grasso
Adriana Gambardella
Amit Grover
Kari Högstrand
Allegra M. Lord
Alejandra Sanjuan-Pla
Petter S. Woll
Claus Nerlov
Sten Eirik W. Jacobsen
机构：
[1] Haematopoietic Stem Cell Laboratory,Radcliffe Department of Medicine
[2] MRC Weatherall Institute of Molecular Medicine,Radcliffe Department of Medicine
[3] University of Oxford,Department of Cell and Molecular Biology
[4] MRC Molecular Haematology Unit,Department of Medicine Huddinge
[5] MRC Weatherall Institute of Molecular Medicine,Division of Experimental Hematology and Cancer Biology
[6] University of Oxford,Hematology Research Group
[7] Wallenberg Institute for Regenerative Medicine,undefined
[8] Karolinska Institutet,undefined
[9] Karolinska Institutet,undefined
[10] Center for Hematology and Regenerative Medicine,undefined
[11] Karolinska Institutet,undefined
[12] Karolinska University Hospital,undefined
[13] Cincinnati Children's Hospital Medical Center and University of Cincinnati,undefined
[14] Instituto de Investigación Sanitaria La Fe,undefined
来源：
Nature | 2018年 / 554卷
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摘要：
Analysis of transplantation of single haematopoietic stem cells in mice defines stable lineage-restricted fates in long-term self-renewing multipotent stem cells, including a class of multipotent stem cells that exclusively replenishes the megakaryocyte/platelet lineage.
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页码：106 / 111
页数：5
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