Acid sensing by the Drosophila olfactory system

被引:0
|
作者
Minrong Ai
Soohong Min
Yael Grosjean
Charlotte Leblanc
Rati Bell
Richard Benton
Greg S. B. Suh
机构
[1] Molecular Neurobiology Program,Department of Cell Biology
[2] Skirball Institute of Biomolecular Medicine,undefined
[3] New York University,undefined
[4] School of Medicine,undefined
[5] Center for Integrative Genomics,undefined
[6] Faculty of Biology and Medicine,undefined
[7] University of Lausanne,undefined
[8] Present addresses: Centre des Sciences du Goût et de l’Alimentation,undefined
[9] UMR-6265 CNRS,undefined
[10] UMR-1324 INRA,undefined
[11] Université de Bourgogne,undefined
[12] 6 Boulevard Gabriel,undefined
[13] 21000 Dijon,undefined
[14] France (Y.G.); Université Paris Diderot – Paris 7,undefined
[15] 16 rue Marguerite Duras,undefined
[16] 75013 Paris,undefined
[17] France (C.L.).,undefined
来源
Nature | 2010年 / 468卷
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摘要
We are familiar with the unpleasant and often irritating odour associated with acids, but whereas acid receptors are known to underlie the detection of sour tastes, no acid-sensing neurons were known in the olfactory system. Greg Suh and colleagues now report the identification of such neurons in the olfactory system of the fruitfly, Drosophila melanogaster. Acid sensing also requires the transmembrane protein IR64a to be expressed in those neurons. IR64a is not sufficient by itself to determine acid recognition, but its requirement is the first known function for a member of the recently discovered ionotropic receptor family of putative odorant receptors.
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页码:691 / 695
页数:4
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