Radiofrequency thermal ablation of metastatic neuroendocrine tumors in the liver

被引：13
作者：
Mazzaglia P.J. [1 ]
Berber E. [1 ]
Siperstein A.E. [1 ]
机构：
[1] Department of Surgery A-80, Cleveland Clinic Foundation, Cleveland, OH
来源：
Current Treatment Options in Oncology | 2007年 / 8卷 / 4期
关键词：
Octreotide; Endocrine Tumor; Lanreotide; Medullary Thyroid Cancer; Carcinoid Syndrome;
D O I：
10.1007/s11864-007-0038-9
中图分类号：
学科分类号：
摘要：
In our armamentarium against neuroendocrine hepatic metastases, radiofrequency thermal ablation has proven to play a valuable role. Patients with neuroendocrine malignancies that progress to hepatic metastases may suffer not only from the hormonal sequelae of their disease, but also face the specter of death within several years from progressive hepatic replacement. For the majority of these patients who are not surgical candidates due to the extent of liver involvement, radiofrequency thermal ablation represents a low-risk treatment modality effective at both symptom alleviation and survival prolongation. Utilizing a laparoscopic approach guided by intra-operative ultrasound, effective tumor ablation can be achieved with minimal morbidity and low rates of local tumor recurrence. © Current Science Inc. 2007.
引用
收藏
页码：322 / 330
页数：8
相关论文
共 30 条
  • [1] Touzios J.G., Kiely J.M., Pitt S.C., Et al., Neuroendocrine hepatic metastases: Does aggressive management improve survival?, Ann Surg, 241, 5, pp. 776-783, (2005)
  • [2] Sarmiento J.M., Heywood G., Rubin J., Et al., Surgical treatment of neuroendocrine metastases to the liver: A plea for resection to increase survival, J Am Coll Surg, 197, 1, pp. 29-37, (2003)
  • [3] Carty S.E., Jensen R.T., Norton J.A., Prospective study of aggressive resection of metastatic pancreatic endocrine tumors, Surgery, 112, 6, pp. 1024-1031, (1992)
  • [4] Lounsberry W., Goldschmidt V., Linke C., The early histologic changes following electrocoagulation, J Urol, 86, pp. 291-297, (1961)
  • [5] Buscarini L., Rossi S., Fornari F., Et al., Laparoscopic ablation of liver adenoma by radiofrequency electrocautery, Gastrointest Endosc, 41, 1, pp. 68-70, (1995)
  • [6] Rossi S., Di Stasi M., Buscarini E., Et al., Percutaneous radiofrequency interstitial thermal ablation in the treatment of small hepatocellular carcinoma, Cancer J Sci Am, 1, 1, pp. 73-81, (1995)
  • [7] Berber E., Flesher N.L., Siperstein A.E., Initial clinical evaluation of the RITA 5-centimeter radiofrequency thermal ablation catheter in the treatment of liver tumors, Cancer J Sci Am, 6, S4, (2000)
  • [8] Berber E., Siperstein A.E., Perioperative outcome after laparoscopic radiofrequency ablation of liver tumors: An analysis of 521 cases, Surg Endosc, 21, 4, pp. 613-618, (2007)
  • [9] Mazzaglia P.J., Berber E., Milas M., Siperstein A.E., Laparoscopic radiofrequency ablation of neuroendocrine liver metastases: A 10-year experience evaluating predictors of survival, Surgery, 142, 1, pp. 10-19, (2007)
  • [10] Berber E., Flesher N., Siperstein A.E., Laparoscopic radiofrequency ablation of neuroendocrine liver metastases, World J Surg, 26, 8, pp. 985-990, (2002)
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