Chitotriosidase as a marker of disease activity in sarcoidosis

被引：0
|
作者：
Jürgen Brunner
Sabine Scholl-Bürgi
Martina Prelog
Lothar-Bernd Zimmerhackl
机构：
[1] Innsbruck Medical School,Division of Neonatology and Neuropediatrics, Department of Pediatrics
[2] Innsbruck Medical School,Division of Rheumatology, Nephrology, Infectiology and Endocrinology, Department of Pediatrics
来源：
Rheumatology International | 2007年 / 27卷
关键词：
Juvenile sarcoidosis; Chitotriosidase;
D O I：
暂无
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学科分类号：
摘要：
Sarcoidosis is a chronic granulomatous inflammation. The clinical spectrum in childhood is heterogeneous. Angiotensin converting enzyme activity is used as a marker for disease activity. Human chitotriosidase is produced in macrophages. In this study, serum chitotriosidase levels were significantly higher in active sarcoidosis than in inactive disease or healthy controls. Serum chitotriosidase concentrations may be a useful marker for monitoring disease activity in sarcoidosis.
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