Leukocyte-endothelial interactions in pial arterioles and venules on development of cerebral ischemia in rats

被引：2
|
作者：
Mel'nikova N.N. [1 ]
机构：
[1] I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, 199034 St. Petersburg
来源：
Neuroscience and Behavioral Physiology | 2009年 / 39卷 / 2期
基金：
俄罗斯基础研究基金会;
关键词：
Ischemia; Leukocyte adhesion; Microcirculation; Pial microvessels;
D O I：
10.1007/s11055-009-9110-1
中图分类号：
学科分类号：
摘要：
In vivo microscopy was used to study the interaction between leukocytes and the pial venular and arteriolar endothelium in rats during cerebral ischemia evoked by bilateral ligation occlusion of the carotid arteries. Specimens were obtained from 40 arterioles and 30 venules (diameter up to 40 μm) of the pia mater from Wistar rats (n = 7) subjected to ischemia for 5 h to respiratory arrest. The experimental data demonstrated significant differences in changes in the adhesion of leukocytes to the endothelium of arterial and venous microvessels during the development of hypoxia. © 2009 Springer Science+Business Media, Inc.
引用
收藏
页码：167 / 171
页数：4
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