Undetectable circulating tumor DNA (ctDNA) levels correlate with favorable outcome in metastatic melanoma patients treated with anti-PD1 therapy

被引：0
|
作者：
Teofila Seremet
Yanina Jansen
Simon Planken
Hassan Njimi
Mélanie Delaunoy
Hakim El Housni
Gil Awada
Julia Katharina Schwarze
Marleen Keyaerts
Hendrik Everaert
Danielle Lienard
Véronique Del Marmol
Pierre Heimann
Bart Neyns
机构：
[1] Universitair Ziekenhuis Brussel,Department of Medical Oncology
[2] Vrije Universiteit Brussel (VUB),Department of Dermatology
[3] Hôpital Erasme,Department of Biomedical Statistics
[4] Université Libre de Bruxelles (ULB),Laboratory of Molecular Biology in Haemato
[5] Université Libre de Bruxelles (ULB),oncology
[6] LHUB-ULB,Department of Nuclear Medicine
[7] Hôpital Erasme,undefined
[8] Université Libre de Bruxelles (ULB),undefined
[9] Universitair Ziekenhuis Brussel,undefined
[10] Vrije Universiteit Brussel (VUB),undefined
来源：
Journal of Translational Medicine | / 17卷
关键词：
Translational research; Liquid biopsy; Circulating tumor DNA; Monitoring; Immunotherapy; Metastatic melanoma; BRAF/NRAS mutations monitoring;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Activity and safety of radiotherapy with anti-PD-1 drug therapy in patients with metastatic melanoma
    Liniker, E.
    Menzies, A. M.
    Kong, B. Y.
    Cooper, A.
    Ramanujam, S.
    Lo, S.
    Kefford, R. F.
    Fogarty, G. B.
    Guminski, A.
    Wang, T. W.
    Carlino, M. S.
    Hong, A.
    Long, G. V.
    ONCOIMMUNOLOGY, 2016, 5 (09):
  • [32] Functional Gene Expression Signatures from On-Treatment Tumor Specimens Predict Anti-PD1 Blockade Response in Metastatic Melanoma
    Chen, Shuzhao
    Zhang, Limei
    Lin, Haocheng
    Liang, Yang
    Wang, Yun
    BIOMOLECULES, 2023, 13 (01)
  • [33] Circulating Tumour DNA for Monitoring Treatment Response to Anti-PD-1 Immunotherapy in Melanoma Patients
    Ashida, Atsuko
    Sakaizawa, Kaori
    Uhara, Hisashi
    Okuyama, Ryuhei
    ACTA DERMATO-VENEREOLOGICA, 2017, 97 (10) : 1212 - 1218
  • [34] Endocrine-related adverse events in a large series of cancer patients treated with anti-PD1 therapy
    Rubino, Rossella
    Marini, Andrea
    Roviello, Giandomenico
    Presotto, Elena Margherita
    Desideri, Isacco
    Ciardetti, Isabella
    Brugia, Marco
    Pimpinelli, Nicola
    Antonuzzo, Lorenzo
    Mini, Enrico
    Livi, Lorenzo
    Maggi, Mario
    Peri, Alessandro
    ENDOCRINE, 2021, 74 (01) : 172 - 179
  • [35] Endocrine-related adverse events in a large series of cancer patients treated with anti-PD1 therapy
    Rossella Rubino
    Andrea Marini
    Giandomenico Roviello
    Elena Margherita Presotto
    Isacco Desideri
    Isabella Ciardetti
    Marco Brugia
    Nicola Pimpinelli
    Lorenzo Antonuzzo
    Enrico Mini
    Lorenzo Livi
    Mario Maggi
    Alessandro Peri
    Endocrine, 2021, 74 : 172 - 179
  • [36] Germline Variation in PDCD1 Is Associated with Overall Survival in Patients with Metastatic Melanoma Treated with Anti-PD-1 Monotherapy
    de With, Mirjam
    Hurkmans, Daan P.
    Oomen-de Hoop, Esther
    Lalouti, Ayoub
    Bins, Sander
    El Bouazzaoui, Samira
    van Brakel, Mandy
    Debets, Reno
    Aerts, Joachim G. J. V.
    van Schaik, Ron H. N.
    Mathijssen, Ron H. J.
    van der Veldt, Astrid A. M.
    CANCERS, 2021, 13 (06) : 1 - 13
  • [37] Tumor mutation burden and circulating tumor DNA in combined CTLA-4 and PD-1 antibody therapy in metastatic melanoma - results of a prospective biomarker study
    Forschner, Andrea
    Battke, Florian
    Hadaschik, Dirk
    Schulze, Martin
    Weissgraeber, Stephanie
    Han, Chung-Ting
    Kopp, Maria
    Frick, Maximilian
    Klumpp, Bernhard
    Tietze, Nicola
    Amaral, Teresa
    Martus, Peter
    Sinnberg, Tobias
    Eigentler, Thomas
    Kelm, Ulrike
    Garbe, Claus
    Doecker, Dennis
    Biskup, Saskia
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
  • [38] Efficacy and safety of anti-PD1 monotherapy or in combination with ipilimumab after BRAF/MEK inhibitors in patients with BRAF mutant metastatic melanoma
    Pires da Silva, Ines
    Zakria, Danny
    Ahmed, Tasnia
    Trojanello, Claudia
    Dimitriou, Florentia
    Allayous, Clara
    Gerard, Camille
    Zimmer, Lisa
    Lo, Serigne
    Michielin, Olivier
    Lebbe, Celeste
    Mangana, Johanna
    Ascierto, Paolo Antonio
    Johnson, Douglas B.
    Carlino, Matteo
    Menzies, Alexander
    Long, Georgina
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 (07)
  • [39] Older melanoma patients aged 75 and above retain responsiveness to anti-PD1 therapy: results of a retrospective single-institution cohort study
    Ibrahim, Tony
    Mateus, Christine
    Baz, Maria
    Robert, Caroline
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2018, 67 (10) : 1571 - 1578
  • [40] Efficacy of ipilimumab after anti-PD-1 therapy in sequential treatment of metastatic melanoma patients - Real world evidence
    Cybulska-Stopa, Bozena
    Rogala, Pawel
    Czarnecka, Anna M.
    Lugowska, Iwona
    Teterycz, Pawel
    Galus, Lukasz
    Rajczykowski, Marcin
    Dawidowska, Anna
    Piejko, Karolina
    Suwinski, Rafal
    Mackiewicz, Jacek
    Rutkowski, Piotr
    ADVANCES IN MEDICAL SCIENCES, 2020, 65 (02): : 316 - 323
12345