Undetectable circulating tumor DNA (ctDNA) levels correlate with favorable outcome in metastatic melanoma patients treated with anti-PD1 therapy

被引:0
|
作者
Teofila Seremet
Yanina Jansen
Simon Planken
Hassan Njimi
Mélanie Delaunoy
Hakim El Housni
Gil Awada
Julia Katharina Schwarze
Marleen Keyaerts
Hendrik Everaert
Danielle Lienard
Véronique Del Marmol
Pierre Heimann
Bart Neyns
机构
[1] Universitair Ziekenhuis Brussel,Department of Medical Oncology
[2] Vrije Universiteit Brussel (VUB),Department of Dermatology
[3] Hôpital Erasme,Department of Biomedical Statistics
[4] Université Libre de Bruxelles (ULB),Laboratory of Molecular Biology in Haemato
[5] Université Libre de Bruxelles (ULB),oncology
[6] LHUB-ULB,Department of Nuclear Medicine
[7] Hôpital Erasme,undefined
[8] Université Libre de Bruxelles (ULB),undefined
[9] Universitair Ziekenhuis Brussel,undefined
[10] Vrije Universiteit Brussel (VUB),undefined
来源
Journal of Translational Medicine | / 17卷
关键词
Translational research; Liquid biopsy; Circulating tumor DNA; Monitoring; Immunotherapy; Metastatic melanoma; BRAF/NRAS mutations monitoring;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Undetectable circulating tumor DNA (ctDNA) levels correlate with favorable outcome in metastatic melanoma patients treated with anti-PD1 therapy
    Seremet, Teofila
    Jansen, Yanina
    Planken, Simon
    Njimi, Hassan
    Delaunoy, Melanie
    El Housni, Hakim
    Awada, Gil
    Schwarze, Julia Katharina
    Keyaerts, Marleen
    Everaert, Hendrik
    Lienard, Danielle
    Del Marmol, Veronique
    Heimann, Pierre
    Neyns, Bart
    JOURNAL OF TRANSLATIONAL MEDICINE, 2019, 17 (01)
  • [2] Circulating Tumor DNA Early Kinetics Predict Response of Metastatic Melanoma to Anti-PD1 Immunotherapy: Validation Study
    Herbreteau, Guillaume
    Vallee, Audrey
    Knol, Anne-Chantal
    Theoleyre, Sandrine
    Quereux, Gaelle
    Varey, Emilie
    Khammari, Amir
    Dreno, Brigitte
    Denis, Marc G.
    CANCERS, 2021, 13 (08)
  • [3] Illustrative cases for monitoring by quantitative analysis of BRAF/NRAS ctDNA mutations in liquid biopsies of metastatic melanoma patients who gained clinical benefits from anti-PD1 antibody therapy
    Seremet, Teofila
    Planken, Simon
    Schreuer, Max
    Jansen, Yanina
    Delaunoy, Melanie
    El Housni, Hakim
    Lienard, Danielle
    Del Marmol, Veronique
    Heimann, Pierre
    Neyns, Bart
    MELANOMA RESEARCH, 2018, 28 (01) : 65 - 70
  • [4] Circulating tumour DNA predicts response to anti-PD1 antibodies in metastatic melanoma
    Lee, J. H.
    Long, G. V.
    Boyd, S.
    Lo, S.
    Menzies, A. M.
    Tembe, V.
    Guminski, A.
    Jakrot, V.
    Scolyer, R. A.
    Mann, G. J.
    Kefford, R. F.
    Carlino, M. S.
    Rizos, H.
    ANNALS OF ONCOLOGY, 2017, 28 (05) : 1130 - 1136
  • [5] TGF-β mRNA levels in circulating extracellular vesicles are associated with response to anti-PD1 treatment in metastatic melanoma
    Crucitta, Stefania
    Cucchiara, Federico
    Marconcini, Riccardo
    Bulleri, Alessandra
    Manacorda, Simona
    Capuano, Annalisa
    Cioni, Dania
    Nuzzo, Amedeo
    de Jonge, Evert
    Mathjissen, Ron H. J.
    Neri, Emanuele
    van Schaik, Ron H. N.
    Fogli, Stefano
    Danesi, Romano
    Del Re, Marzia
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2024, 11
  • [6] Circulating extracellular vesicles are monitoring biomarkers of anti-PD1 response and enhancer of tumor progression and immunosuppression in metastatic melanoma
    Serrati, Simona
    Di Fonte, Roberta
    Porcelli, Letizia
    De Summa, Simona
    De Risi, Ivana
    Fucci, Livia
    Ruggieri, Eustachio
    Marvulli, Tommaso Maria
    Strippoli, Sabino
    Fasano, Rossella
    Rafaschieri, Tania
    Guida, Gabriella
    Guida, Michele
    Azzariti, Amalia
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2023, 42 (01)
  • [7] Circulating extracellular vesicles are monitoring biomarkers of anti-PD1 response and enhancer of tumor progression and immunosuppression in metastatic melanoma
    Simona Serratì
    Roberta Di Fonte
    Letizia Porcelli
    Simona De Summa
    Ivana De Risi
    Livia Fucci
    Eustachio Ruggieri
    Tommaso Maria Marvulli
    Sabino Strippoli
    Rossella Fasano
    Tania Rafaschieri
    Gabriella Guida
    Michele Guida
    Amalia Azzariti
    Journal of Experimental & Clinical Cancer Research, 42
  • [8] Immune-related adverse events correlate with improved survival in patients undergoing anti-PD1 immunotherapy for metastatic melanoma
    Alice Indini
    Lorenza Di Guardo
    Carolina Cimminiello
    Michele Prisciandaro
    Giovanni Randon
    Filippo De Braud
    Michele Del Vecchio
    Journal of Cancer Research and Clinical Oncology, 2019, 145 : 511 - 521
  • [9] Immune-related adverse events correlate with improved survival in patients undergoing anti-PD1 immunotherapy for metastatic melanoma
    Indini, Alice
    Di Guardo, Lorenza
    Cimminiello, Carolina
    Prisciandaro, Michele
    Randon, Giovanni
    De Braud, Filippo
    Del Vecchio, Michele
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2019, 145 (02) : 511 - 521
  • [10] CT texture analysis as a predictor of favorable response to anti-PD1 monoclonal antibodies in metastatic skin melanoma
    Bonnin, Angele
    Durot, Carole
    Barat, Maxime
    Djelouah, Manel
    Grange, Florent
    Mule, Sebastien
    Soyer, Philippe
    Hoeffel, Christine
    DIAGNOSTIC AND INTERVENTIONAL IMAGING, 2022, 103 (02) : 97 - 102