Synthesis of enantiomers of N-(2-aminopurin-6-yl)amino acids

被引：0
作者：
V. P. Krasnov
A. Yu. Vigorov
D. A. Gruzdev
G. L. Levit
A. M. Demin
I. A. Nizova
A. A. Tumashov
L. Sh. Sadretdinova
E. B. Gorbunov
V. N. Charushin
机构：
[1] Ural Branch of the Russian Academy of Sciences,I. Ya. Postovsky Institute of Organic Synthesis
来源：
Russian Chemical Bulletin | 2015年 / 64卷
关键词：
purines; amino acids; enantiomers; racemization; high performance liquid chromatography;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Nonracemic N-(2-aminopurin-6-yl)-substituted amino acids were synthesized by nucleophilic substitution of chlorine atom in 2-acetamido-6-chloropurine upon treatment with amino acid tert-butyl esters and subsequent removal of protecting groups. Their enantiomeric composition was determined by HPLC on chiral stationary phases.
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页码：2106 / 2113
页数：7
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