Ex vivo expansion of hematopoietic stem cells in bioreactors

被引:1
|
作者
J.M.S. Cabral
机构
[1] Instituto Superior Técnico,Centro de Engenharia Biológica e Química
来源
Biotechnology Letters | 2001年 / 23卷
关键词
differentiation; expansion; hollow fiber reactors; packed bed reactors; perfusion reactors; stem cells; stirred reactors;
D O I
暂无
中图分类号
学科分类号
摘要
The in vitro culture of human hematopoietic stem cells in different types of bioreactors is reviewed. After a brief description of the hematopoiesis and stem cells biology, the selection of growth medium for stem cells is evaluated as well as the parameters to be controlled for ex vivo expansion and differentiation of stem cells. Several types of bioreactors for in vitro stem cell culture are discussed and compared.
引用
收藏
页码:741 / 751
页数:10
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