Ex vivo expansion of hematopoietic stem cells in bioreactors

被引：1
|
作者：
J.M.S. Cabral
机构：
[1] Instituto Superior Técnico,Centro de Engenharia Biológica e Química
来源：
Biotechnology Letters | 2001年 / 23卷
关键词：
differentiation; expansion; hollow fiber reactors; packed bed reactors; perfusion reactors; stem cells; stirred reactors;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The in vitro culture of human hematopoietic stem cells in different types of bioreactors is reviewed. After a brief description of the hematopoiesis and stem cells biology, the selection of growth medium for stem cells is evaluated as well as the parameters to be controlled for ex vivo expansion and differentiation of stem cells. Several types of bioreactors for in vitro stem cell culture are discussed and compared.
引用
收藏
页码：741 / 751
页数：10
相关论文
共 50 条
  • [21] The impact of parathyroid hormone treated mesenchymal stem cells on ex-vivo expansion of cord blood hematopoietic stem cells
    Esmaeili, Mohammadhosein
    Niazi, Vahid
    Pourfathollah, Ali Akbar
    Hosseini, Mir Kamran Mousavi
    Nakhlestani, Mozhdeh
    Golzadeh, Khadijeh
    Taheri, Mohammad
    Ghafouri-Fard, Soudeh
    Atarodi, Kamran
    GENE REPORTS, 2019, 17
  • [22] Marrow mesenchymal stem cells transduced with TPO/FL genes as support for ex vivo expansion of hematopoietic stem/progenitor cells
    C.-g. Xie
    J.-f. Wang
    Y. Xiang
    B.-b. Jia
    L.-y. Qiu
    L.-j. Wang
    G.-z. Wang
    G.-p. Huang
    Cellular and Molecular Life Sciences CMLS, 2005, 62 : 2495 - 2507
  • [23] Optimizing BIO feeding strategy promotes ex vivo expansion of human hematopoietic stem and progenitor cells
    Sun, Qihao
    Zhou, Yiran
    Zhu, Xuejun
    Tan, Wen-Song
    Cai, Haibo
    JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2021, 131 (02) : 190 - 197
  • [24] RXR Negatively Regulates Ex Vivo Expansion of Human Cord Blood Hematopoietic Stem and Progenitor Cells
    Yuting Jin
    Jie Huang
    Qin Wang
    Jiefeng He
    Yincheng Teng
    Rongzhen Jiang
    Hal E. Broxmeyer
    Bin Guo
    Stem Cell Reviews and Reports, 2021, 17 : 1456 - 1464
  • [25] The Effects of X-Irradiation on Ex Vivo Expansion of Cryopreserved Human Hematopoietic Stem/Progenitor Cells
    Hayashi, Naoki
    Takahashi, Kenji
    Kashiwakura, Ikuo
    JOURNAL OF RADIATION RESEARCH, 2010, 51 (02) : 137 - 144
  • [26] Ex vivo expansion of hematopoietic stein cells: Concept and clinical benefit
    Ivanovic, Z.
    Boiron, J. -M.
    TRANSFUSION CLINIQUE ET BIOLOGIQUE, 2009, 16 (5-6) : 489 - 500
  • [27] Cell processing engineering for ex-vivo expansion of hematopoietic cells
    Takagi, M
    JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2005, 99 (03) : 189 - 196
  • [28] Cytokine combinations for the in-vivo and ex-vivo expansion of hematopoietic progenitor cells
    Geissler, K
    Wagner, T
    ACTA MEDICA AUSTRIACA, 2000, 27 : 21 - 24
  • [29] Stirred bioreactors for the expansion of adult pancreatic stem cells
    Serra, Margarida
    Brito, Catarina
    Leite, Sofia B.
    Gorjup, Erwin
    von Briesen, Hagen
    Carrondo, Manuel J. T.
    Alves, Paula M.
    ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER, 2009, 191 (01) : 104 - 115
  • [30] NOTCH-mediated ex vivo expansion of human hematopoietic stem and progenitor cells by culture under hypoxia
    Araki, Daisuke
    Fu, Jian Fei
    Huntsman, Heather
    Cordes, Stefan
    Seifuddin, Fayaz
    Alvarado, Luigi J.
    Cheruku, Patali S.
    Cash, Ayla
    Traba, Javier
    Li, Yuesheng
    Pirooznia, Mehdi
    Smith, Richard H.
    Larochelle, Andre
    STEM CELL REPORTS, 2021, 16 (09): : 2336 - 2350
12345