Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability

被引：0
作者：
David M. Nelson
Farah Jaber-Hijazi
John J. Cole
Neil A. Robertson
Jeffrey S. Pawlikowski
Kevin T. Norris
Steven W. Criscione
Nikolay A. Pchelintsev
Desiree Piscitello
Nicholas Stong
Taranjit Singh Rai
Tony McBryan
Gabriel L. Otte
Colin Nixon
William Clark
Harold Riethman
Hong Wu
Gunnar Schotta
Benjamin A. Garcia
Nicola Neretti
Duncan M. Baird
Shelley L. Berger
Peter D. Adams
机构：
[1] Institute of Cancer Sciences,Division of Cancer and Genetics, School of Medicine
[2] University of Glasgow,Department of Molecular Biology, Cell Biology and Biochemistry
[3] Beatson Institute for Cancer Research,Institute of Biomedical and Environmental Health Research
[4] Cardiff University,Epigenetics Program, Department of Cell and Developmental Biology, Perelman School of Medicine
[5] Brown University,Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine
[6] The Wistar Institute,undefined
[7] University of the West of Scotland,undefined
[8] University of Pennsylvania,undefined
[9] Fox Chase Cancer Center,undefined
[10] Ludwig Maximilians University and Munich Center for Integrated Protein Science (CiPSM),undefined
[11] Biomedical Center,undefined
[12] University of Pennsylvania,undefined
来源：
Genome Biology | / 17卷
关键词：
Cell senescence; Chromatin; Tumor suppression; SUV420H2/H4K20me3;
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