Anaphylactic reaction associated with Ranitidine in a patient with acute pancreatitis: A case report

被引：9

作者：

Rethnam U. ^{[1
]}

Yesupalan R.S. ^{[1
]}

机构：

[1] Department of Orthopaedics, Glan Clwyd Hospital, Rhyl

来源：

Journal of Medical Case Reports | / 1卷 / 1期

关键词：

Acute Pancreatitis; Metronidazole; Ranitidine; Anaphylactic Reaction; Inotropic Support;

D O I：

10.1186/1752-1947-1-75

中图分类号：

学科分类号：

摘要：

Ranitidine is a widely used drug and is known to be well tolerated. This case report illustrates a severe anaphylactic reaction after a single intravenous dose of 50 mgs of ranitidine and highlights this unusual but life threatening adverse reaction. The patient: A 56 year old female with acute pancreatitis and a known allergy to metronidazole and buscopan developed an anaphylaxis few minutes following the injection of ranitidine for epigastric discomfort. She went on to develop anaphylactic shock and a cardiorespiratory arrest. Management: She was managed with adrenaline, hydrocortisone andventilatory support following which she had a full recovery. Conclusion: Awareness of this rare but life threatening adverse reaction to a commonly used drug can avoid being caught unaware. © 2007 Rethnam and Yesupalan; licensee BioMed Central Ltd.

引用

共 5 条

[1] Powell J.A., Maycock E.J., Anaphylactoid reaction to ranitidine in an obstetric patient, Anaesth Intensive Care, 21, 5, pp. 702-703, (1993)
[2] Barry J.E., Madan R., Hewitt P.B., Anaphylactoid reaction to ranitidine in an obstetric patient, Anaesthesia, 47, 4, pp. 360-361, (1992)
[3] Greer I.A., Fellows K., Anaphylactoid reaction to ranitidine in labour, Br J Clin Pract, 44, 2, (1990)
[4] Natsch S., Vinkins M.H., Voogt A.K., Mees E.B., Meyboom R.H.B., Anaphylactic reactions to proton-pump inhibitors, Ann Pharmacother, 34, pp. 474-476, (2000)
[5] Demirkan K., Bozkurt B., Karakaya G., Kalyoncu A.F., Anaphylactic Reaction to Drugs Commonly Used for Gastrointestinal System Diseases: 3 Case Reports and Review of the Literature, J Investig Allergol Clin Immunol, 16, 3, pp. 203-209, (2006)

← 1 →