Prediction of tissue-specific effects of gene knockout on apoptosis in different anatomical structures of human brain

被引:0
作者
Evgeny D Petrovskiy
Olga V Saik
Evgeny S Tiys
Inna N Lavrik
Nikolay A Kolchanov
Vladimir A Ivanisenko
机构
[1] The Siberian Branch of the Russian Academy of Sciences,The Federal Research Center Institute of Cytology and Genetics
[2] The Siberian Branch of the Russian Academy of Sciences,International Tomography Center
[3] Otto von Guericke University Magdeburg,Medical Faculty, Department Translational Inflammation Research, Institute of Experimental Internal Medicine, Pfälzer Platz
来源
BMC Genomics | / 16卷
关键词
Gene expression; Machine learning; Regression models; Knockout effect prediction; Human brain; Drug target prediction; Neurodegenerative diseases;
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  • [1] Hawrylycz MJ(2012)An anatomically comprehensive atlas of the adult human brain transcriptome Nature 489 391-399
  • [2] Lein ES(2004)Gene expression nervous system atlas (GENSAT) Nat Neurosci 7 483-210
  • [3] Guillozet-Bongaarts AL(2006)BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system PLoS Biol 4 497-65
  • [4] Shen EH(2002)Gene Expression Omnibus: NCBI gene expression and hybridization array data repository Nucleic Acids Res 30 207-103
  • [5] Ng L(2014)A review on the computational approaches for gene regulatory network construction Comput Biol Med 48 55-103
  • [6] Miller JA(2002)Modeling and simulation of genetic regulatory systems: a literature review J Comput Biol 9 67-52
  • [7] van de Lagemaat LN(2013)Modeling of gene regulatory networks: A review J Biomed Sci Eng 6 223-187
  • [8] Smith KA(2009)Gene regulatory network inference: data integration in dynamic models--a review Biosystems 96 86-342
  • [9] Ebbert A(2007)Inferring cellular networks - a review BMC Bioinformatics 8 S5-804
  • [10] Riley ZL(1999)Linear modeling of mRNA expression levels during CNS development and injury Pacific symposium on biocomputing 4 41-805