Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma

被引:0
|
作者
Lina Y Dimberg
Anna Dimberg
Karolina Ivarsson
Mårten Fryknäs
Linda Rickardson
Gerard Tobin
Simon Ekman
Rolf Larsson
Urban Gullberg
Kenneth Nilsson
Fredrik Öberg
Helena Jernberg Wiklund
机构
[1] Rudbeck Laboratory,Department of Immunology, Genetics and Pathology
[2] Uppsala University,Department of Medical Sciences
[3] Uppsala University,Department of Laboratory Medicine
[4] Lund University,undefined
来源
BMC Cancer | / 12卷
关键词
Hematopoetic malignancies; Multiple myeloma; Apoptosis; IFN; Stat1; Stat3; Drug sensitivity;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma
    Dimberg, Lina Y.
    Dimberg, Anna
    Ivarsson, Karolina
    Fryknas, Marten
    Rickardson, Linda
    Tobin, Gerard
    Ekman, Simon
    Larsson, Rolf
    Gullberg, Urban
    Nilsson, Kenneth
    Oberg, Fredrik
    Wiklund, Helena Jernberg
    BMC CANCER, 2012, 12
  • [2] IL-10 INDUCES STAT1 AND STAT3 ACTIVATION IN CELLS
    WEBERNORDT, RM
    GREENLUND, AC
    DARNELL, JE
    SCHREIBER, RD
    BLOOD, 1994, 84 (10) : A223 - A223
  • [3] Thienotriazolopyrimidine Derivatives Inhibit STAT3 Activation Induced by IL-6
    Lee, Seung Woong
    Oh, Hyun-Mee
    Rho, Mun-Chual
    Song, Yang-Heon
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2014, 35 (08) : 2570 - 2572
  • [4] Regulation of the human mu-opioid receptor gene by IL-6, STAT1 and STAT3
    Börner, C
    Kraus, J
    Höllt, V
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2004, 369 : R74 - R74
  • [5] Angiopathic activity of LRG1 is induced by the IL-6/STAT3 pathway
    Athina Dritsoula
    Laura Dowsett
    Camilla Pilotti
    Marie N. O’Connor
    Stephen E. Moss
    John Greenwood
    Scientific Reports, 12
  • [6] IL-10 ACTIVATES STAT1 AND STAT3
    WEBERNORDT, RM
    GREENLUND, AC
    MOORE, KW
    DARNELL, JE
    SCHREIER, RD
    FASEB JOURNAL, 1995, 9 (04): : A772 - A772
  • [7] IL-6 Activated JAK/STAT3 Pathway and Sensitivity to Hsp90 Inhibitors in Multiple Myeloma
    Kolosenko, I.
    Grander, D.
    Tamm, K. P.
    CURRENT MEDICINAL CHEMISTRY, 2014, 21 (26) : 3042 - 3047
  • [8] Synthesis of Thienopyrimidine Derivatives as Inhibitors of STAT3 Activation Induced by IL-6
    Jang, Hyun-Jae
    Kim, Sung Min
    Rho, Mun-Chual
    Lee, Seung Woong
    Song, Yang-Heon
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2019, 29 (06) : 856 - 862
  • [9] Activation of STAT1 increases necrosis and apoptosis following ischemia/reperfusion independent of STAT3 activation
    Illigens, BM
    Hsieh, YJ
    Cowan, DB
    McGowan, FX
    Levitsky, S
    McCully, JD
    CIRCULATION, 2004, 110 (17) : 506 - 506
  • [10] Rac1 mediates STAT3 activation by autocrine IL-6
    Faruqi, TR
    Gomez, D
    Bustelo, XR
    Bar-Sagi, D
    Reich, NC
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (16) : 9014 - 9019