Cyst stem cell lineage eIF5 non-autonomously prevents testicular germ cell tumor formation via eIF1A/eIF2γ-mediated pre-initiation complex

被引:0
作者
Zhiran Li
Yunhao Wu
Yangbo Fu
Xia Chen
Xi Zhao
Xiaolong Wu
Yajuan Lu
Hui He
Cong Shen
Bo Zheng
Jun Yu
Fei Sun
机构
[1] Nantong University,Institute of Reproductive Medicine, Medical School
[2] Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City,Department of Obstetrics and Gynecology
[3] Nantong University,Department of Human Anatomy, Medical School
[4] Nanjing Medical University,State Key Laboratory of Reproductive Medicine, Center for Reproduction and Genetics, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, Gusu School
来源
Stem Cell Research & Therapy | / 13卷
关键词
Translation initiation; eIF5; Testicular germ cell tumor; Stem cell niche; Differentiation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 254 条
[21]  
de Rooij DG(2015)A short translational ramp determines the efficiency of protein synthesis BioMed Res Int 10 357-287
[22]  
Hess MW(2019)Eukaryotic translation initiation factors as promising targets in cancer therapy Cell Death Dis 12 323-10014
[23]  
Meng X(2015)The mechanism of eukaryotic translation initiation and principles of its regulation Nat Methods 12 D607-54
[24]  
de Rooij DG(2011)Tuning specific translation in cancer metastasis and synaptic memory: control at the MNK-eIF4E axis BMC Bioinform 47 2498-128
[25]  
Westerdahl K(2019)Targeting the eIF4F translation initiation complex: a critical nexus for cancer development Nucleic Acids Res 13 284-8137
[26]  
Saarma M(2003)eIF3a: a new anticancer drug target in the eIF family Genome Res 16 eabk2432-2063
[27]  
Sariola H(2012)Positive mRNA translational control in germ cells by initiation factor selectivity OMICS 375 10006-360
[28]  
Morimoto H(2022)Srlp is crucial for the self-renewal and differentiation of germline stem cells via RpL6 signals in Science 11 44-141
[29]  
Ogonuki N(2021) testes Clin Transl Med 87 117-7699
[30]  
Kanatsu-Shinohara M(2015)HISAT: a fast spliced aligner with low memory requirements Anal Chem 3 68-22316