Extracellular signal-regulated kinase (ERK) activation is required for itch sensation in the spinal cord

被引：0

作者：

Ling Zhang

Guan-Yu Jiang

Ning-Jing Song

Ying Huang

Jia-Yin Chen

Qing-Xiu Wang

Yu-Qiang Ding

机构：

[1] Tongji University School of Medicine,Key Laboratory of Arrhythmias, Ministry of Education of China, East Hospital

[2] Tongji University School of Medicine,Department of Anatomy and Neurobiology

[3] Shanghai Skin Disease Hospital,Department of Dermatopathology

[4] Tongji University School of Medicine,Department of Anesthesiology, East Hospital

[5] Shanghai International Medical Center,Department of Dermatology

来源：

Molecular Brain | / 7卷

关键词：

Acute itch; Chronic itch; pERK; H1 receptor; Spinal cord; Atopic dermatitis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 272 条

[1] Yamashita H(2010)Comparison of the efficacy of tacrolimus and cyclosporine A in a murine model of dinitrofluorobenzene-induced atopic dermatitis Eur J Pharmacol 645 171-176
[2] Ito T(2006)The neurobiology of itch Nat Rev 7 535-547
[3] Kato H(2003)Itch Lancet 361 690-694
[4] Asai S(2003)Itch: scratching more than the surface Qjm 96 7-26
[5] Tanaka H(2007)A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord Nature 448 700-703
[6] Nagai H(2009)Cellular basis of itch sensation Science (New York, NY 325 1531-1534
[7] Inagaki N(2009)Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus Cell 139 1353-1365
[8] Ikoma A(2010)Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice Neuron 65 886-898
[9] Steinhoff M(2012)TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice J Clin Invest 122 2195-2207
[10] Stander S(2010)Toll-like receptor 7 mediates pruritus Nat Neurosci 13 1460-1462