Harnessing accurate non-homologous end joining for efficient precise deletion in CRISPR/Cas9-mediated genome editing

被引:0
作者
Tao Guo
Yi-Li Feng
Jing-Jing Xiao
Qian Liu
Xiu-Na Sun
Ji-Feng Xiang
Na Kong
Si-Cheng Liu
Guo-Qiao Chen
Yue Wang
Meng-Meng Dong
Zhen Cai
Hui Lin
Xiu-Jun Cai
An-Yong Xie
机构
[1] Zhejiang University School of Medicine,Department of General Surgery, Innovation Center for Minimally Invasive Techniques and Devices, Sir Run Run Shaw Hospital
[2] Zhejiang University School of Medicine,Institute of Translational Medicine
[3] Chongqing General Hospital,Department of General Surgery
[4] Zhejiang University School of Medicine,Multiple Myeloma Treatment Center & Bone Marrow Transplantation Center, The First Affiliated Hospital
来源
Genome Biology | / 19卷
关键词
Paired gRNAs; CRISPR/Cas9; Accurate NHEJ; Templated insertions; Precise deletion; Knockout; Targeted in-frame deletion; Genome editing;
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