Caspase-8 protein cuts a brake on immune defences

被引:2
作者
Brodsky, Igor E. [1 ,2 ]
机构
[1] Univ Penn, Sch Vet Med, Dept Pathobiol, Philadelphia, PA 19104 USA
[2] Univ Penn, Perelman Sch Med, Inst Immunol, Philadelphia, PA 19104 USA
关键词
NF-KAPPA-B; APOPTOSIS; ACTIVATION; EXPRESSION; INHIBITOR; BLOCKADE;
D O I
10.1038/d41586-020-02994-y
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The enzyme caspase-8 can induce cell death or promote survival and the expression of inflammatory proteins. The discovery of a previously unknown caspase-8 target solves one mystery about immune-defence regulation.
引用
收藏
页码:201 / 203
页数:2
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