IRF3: a molecular switch in pathogen responses

被引：0

作者：

Osamu Takeuchi

机构：

[1] Osamu Takeuchi is in the Laboratory of Infection and Prevention,

[2] Institute for Virus Research,undefined

[3] Kyoto University,undefined

[4] Kyoto,undefined

[5] Japan.,undefined

来源：

Nature Immunology | 2012年 / 13卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Antiviral innate immunity often has deleterious effects on the course of bacterial infection. Activation of the transcription factor IRF3 induced by the recognition of double-stranded RNA by RIG-I-like receptors suppresses the Toll-like receptor–induced expression of interleukins 12 and 23 and antibacterial responses.

引用

页码：634 / 635

页数：1

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