New Horizons in Hyperpolarized 13C MRI

被引：0

作者：

Myriam M. Chaumeil

James A. Bankson

Kevin M. Brindle

Shdema Epstein

Ferdia A. Gallagher

Martin Grashei

Caroline Guglielmetti

Joshua D. Kaggie

Kayvan R. Keshari

Stephan Knecht

Christoffer Laustsen

Andreas B. Schmidt

Daniel Vigneron

Yi-Fen Yen

Franz Schilling

机构：

[1] University of California,Department of Physical Therapy and Rehabilitation Science

[2] University of California,Department of Radiology and Biomedical Imaging

[3] The University of Texas MD Anderson Cancer Center,Department of Imaging Physics

[4] Cancer Research UK Cambridge Institute,Department of Biochemistry

[5] University of Cambridge,Department of Radiology

[6] University of Cambridge,Department of Nuclear Medicine, TUM School of Medicine, Klinikum Rechts Der Isar

[7] NVision Imaging Technologies GmbH,Department of Radiology

[8] Addenbrooke’s Hospital,Molecular Pharmacology Program

[9] University of Cambridge,The MR Research Centre, Department of Clinical Medicine

[10] Cancer Research UK Cambridge Centre,Partner Site Freiburg and German Cancer Research Center (DKFZ)

[11] Technical University of Munich,Division of Medical Physics, Department of Diagnostic and Interventional Radiology, Medical Center, Faculty of Medicine

[12] Memorial Sloan Kettering Cancer Center,Department of Chemistry

[13] Memorial Sloan Kettering Cancer Center,Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology

[14] Weill Cornell Graduate School,undefined

[15] Aarhus University,undefined

[16] German Cancer Consortium (DKTK),undefined

[17] University of Freiburg,undefined

[18] Integrative Biosciences (Ibio),undefined

[19] Karmanos Cancer Institute (KCI),undefined

[20] Wayne State University,undefined

[21] Massachusetts General Hospital,undefined

[22] Harvard Medical School,undefined

来源：

Molecular Imaging and Biology | 2024年 / 26卷

关键词：

Consensus; Hyperpolarized 13C; Metabolism; Metabolic imaging; MR spectroscopy; MRI;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Hyperpolarization techniques significantly enhance the sensitivity of magnetic resonance (MR) and thus present fascinating new directions for research and applications with in vivo MR imaging and spectroscopy (MRI/S). Hyperpolarized 13C MRI/S, in particular, enables real-time non-invasive assessment of metabolic processes and holds great promise for a diverse range of clinical applications spanning fields like oncology, neurology, and cardiology, with a potential for improving early diagnosis of disease, patient stratification, and therapy response assessment. Despite its potential, technical challenges remain for achieving clinical translation. This paper provides an overview of the discussions that took place at the international workshop “New Horizons in Hyperpolarized 13C MRI,” in March 2023 at the Bavarian Academy of Sciences and Humanities, Munich, Germany. The workshop covered new developments, as well as future directions, in topics including polarization techniques (particularly focusing on parahydrogen-based methods), novel probes, considerations related to data acquisition and analysis, and emerging clinical applications in oncology and other fields.

引用

页码：222 / 232

页数：10

共 103 条

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