Characterization of a highly pathogenic H5N1 avian influenza virus isolated from ducks in Eastern China in 2011

被引：0
作者：
Wu Hai-bo
Guo Chao-tan
Lu Ru-feng
Xu Li-hua
Wo En-kang
You Jin-biao
Wang Yi-ting
Wang Qiao-gang
Wu Nan-ping
机构：
[1] Zhejiang University,State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, School of Medicine
[2] Zhejiang Academy of Medical Sciences,Institute of Bioengineering
[3] The First Affiliated Hospital of Zhejiang Chinese Medical University,Department of Emergency
[4] Zhejiang Academy of Agricultural Science,Animal Husbandry and Veterinary Institute
来源：
Archives of Virology | 2012年 / 157卷
关键词：
Avian Influenza; H5N1 Virus; Oseltamivir; Avian Influenza Virus; Wild Bird;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This study describes the characterization of seven H5N1 avian influenza viruses from domestic ducks in Eastern China in 2011. Phylogenetic analysis showed these viruses were closely related to an H5N1 virus circulating in wild birds in Hong Kong. Some characteristics of these viruses were similar to those of an H5N1 strain that circulated in China and Vietnam (2003-2004). The virulence of three isolates was examined in chickens and mice, and they were found to be highly pathogenic in chickens but showed low pathogenicity in mice. These results suggest that continued H5N1 surveillance in poultry should be used as an early warning system for avian influenza outbreaks.
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页码：1131 / 1136
页数：5
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