Genetic epidemiology: Juvenile idiopathic arthritis genetics - What's new? What's next?

被引：0
作者：
Wendy Thomson
Rachelle Donn
机构：
[1] University of Manchester,Arthritis Research Campaign Epidemiology Unit, School of Epidemiology and Health Sciences
来源：
Arthritis Research & Therapy | / 4卷
关键词：
candidate genes; cytokines; genetics; juvenile idiopathic arthritis;
D O I：
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摘要：
Studies have established the magnitude of the genetic basis of juvenile idiopathic arthritis (JIA). JIA is a complex genetic condition and the genes that influence susceptibility are actively being sought. A candidate gene approach is being used by several groups. MHC-, cytokine- and T-cell-related genes have all been positively associated with JIA. Here we review some of the latest genetic data, and discuss ways in which JIA genetic research might proceed.
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