YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas

被引:0
作者
Wei Xu
Mingjiong Zhang
Yue Li
Yu Wang
Kai Wang
Qiaoyu Chen
Runjie Zhang
Weiwei Song
Qiqing Huang
Weihong Zhao
Jianqing Wu
机构
[1] The First Affiliated Hospital of Nanjing Medical University,Jiangsu Provincial Key Laboratory of Geriatrics, Department of Geriatrics
[2] Tongji University School of Medicine,Center for Reproductive Medicine, Shanghai First Maternity and Infant Hospital
[3] Nanjing Lishui People’s Hospital,Zhongda Hospital Lishui Branch
[4] Southeast University,undefined
来源
Cancer Cell International | / 21卷
关键词
LUADs; YAP; PTEN/AKT/mTOR; Autophagy;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 204 条
  • [1] Zhao B(2011)The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal Nat Cell Biol 13 877-83
  • [2] Tumaneng K(2015)Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer Cell 163 811-28
  • [3] Guan KL(2007)Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control Genes Dev 21 2747-61
  • [4] Yu FX(2010)A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP) Genes Dev 24 72-85
  • [5] Zhao B(2015)MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway Nat Commun 6 8357-70
  • [6] Guan KL(2017)Mechanobiology of YAP and TAZ in physiology and disease Nat Rev Mol Cell Biol 18 758-803
  • [7] Zhao B(2016)YAP/TAZ at the Roots of Cancer Cancer Cell 29 783-9
  • [8] Wei X(2015)The emerging roles of YAP and TAZ in cancer Nat Rev Cancer 15 73-57
  • [9] Li W(2013)The Hippo pathway and human cancer Nat Rev Cancer 13 246-312
  • [10] Udan RS(2014)The biology of YAP/TAZ: hippo signaling and beyond Physiol Rev 94 1287-27