Regioselective multi-component synthesis of 1H-pyrazolo[3,4-d]pyrimidine-6(7H)-thiones

被引：0
作者：
Shirin Safaei
Iraj Mohammadpoor-Baltork
Ahmad Reza Khosropour
Majid Moghadam
Shahram Tangestaninejad
Valiollah Mirkhani
机构：
[1] University of Isfahan,Catalysis Division, Department of Chemistry
来源：
Molecular Diversity | 2012年 / 16卷
关键词：
Pyrazolo[3,4-; ]pyrimidine-6(7; )-thione; 5-Methyl-1; -pyrazol-3-amine; Arylisothiocyanate; Aldehyde; Multi-component reaction;
D O I：
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中图分类号：
学科分类号：
摘要：
A variety of pyrazolo[3,4-d]pyrimidine-6(7H)-thione derivatives were easily synthesized with a novel, simple, efficient, and regioselective method via three-component condensation reaction of 5-methyl-1H-pyrazol-3-amine, arylisothiocyanates, and aldehydes in the presence of catalytic amount of p-toluenesulfonic acid (p-TSA) in 1-butyl-3-methylimidazolium bromide ionic liquid with excellent yields and short reaction times.
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页码：591 / 600
页数：9
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