Interactions between Diamagnetic Metal Ions and pH-Sensitive Nitroxides

被引:0
作者
Evelyn Zottler
Pawel Cias
Georg Gescheidt
机构
[1] Graz University of Technology,Institute of Physical and Theoretical Chemistry
来源
Applied Magnetic Resonance | 2012年 / 42卷
关键词
Electron Paramagnetic Resonance; Electron Paramagnetic Resonance Spectrum; Nitroxide; Nitroxyl; Spin Probe;
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摘要
Specific interactions between pH-sensitive nitroxide radicals and selected diamagnetic metal ions were investigated. To this end, the influence of different metal salts at varying concentrations on the continuous-wave electron paramagnetic resonance spectra of two imidazoline nitroxides was studied. Among the screened metal ions, Zn(II) most significantly affected the spectral profile, analogous to the effect attributed to protonation of the nitroxide imino nitrogen known from pH studies. Simulations showed the acquired spectra to result from the superposition of the signals of the coordinated and the uncoordinated species. The complex formation between Zn(II) and (4-amino-2,5-dihydro-2,2,5,5-tetramethyl-3-imidazoline-1-yloxyl) was modelled by theoretical methods revealing the rather specific selectivity of the nitroxide toward Zn(II). The results suggest imidazoline nitroxides as promising candidates for the development of new specific metal ion probes.
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页码:283 / 297
页数:14
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