The yin and yang of regulatory T cells and inflammation in RA

被引：0
|
作者：
Clare A. Notley
Michael R. Ehrenstein
机构：
[1] Centre for Rheumatology Research,
[2] Windeyer Institute of Medical Science,undefined
[3] University College London,undefined
来源：
Nature Reviews Rheumatology | 2010年 / 6卷
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D O I：
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学科分类号：
摘要：
Regulatory T (TREG) cells, which function as suppressors of autoimmune responses, are defective in patients with rheumatoid arthritis (RA). In this article, the authors describe the interplay between TREG cells and inflammation in the context of RA, and how a subset of highly potent but unstable TREGcells seems to be induced following tumor necrosis factor blockade.
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页码：572 / 577
页数：5
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