The yin and yang of regulatory T cells and inflammation in RA

被引：0
|
作者：
Clare A. Notley
Michael R. Ehrenstein
机构：
[1] Centre for Rheumatology Research,
[2] Windeyer Institute of Medical Science,undefined
[3] University College London,undefined
来源：
Nature Reviews Rheumatology | 2010年 / 6卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Regulatory T (TREG) cells, which function as suppressors of autoimmune responses, are defective in patients with rheumatoid arthritis (RA). In this article, the authors describe the interplay between TREG cells and inflammation in the context of RA, and how a subset of highly potent but unstable TREGcells seems to be induced following tumor necrosis factor blockade.
引用
收藏
页码：572 / 577
页数：5
相关论文
共 50 条
  • [1] The yin and yang of regulatory T cells and inflammation in RA
    Notley, Clare A.
    Ehrenstein, Michael R.
    NATURE REVIEWS RHEUMATOLOGY, 2010, 6 (10) : 572 - 577
  • [2] Mesenchymal stromal cells and regulatory T cells: the Yin and Yang of peripheral tolerance?
    Burr, Stephen P.
    Dazzi, Francesco
    Garden, Oliver A.
    IMMUNOLOGY AND CELL BIOLOGY, 2013, 91 (01): : 12 - 18
  • [3] The Yin and Yang of CD4+ Regulatory T Cells in Autoimmunity and Cancer
    Galgani, M.
    Di Giacomo, A.
    Matarese, G.
    La Cava, A.
    CURRENT MEDICINAL CHEMISTRY, 2009, 16 (35) : 4626 - 4631
  • [4] The Yin and Yang of regulatory T cells in infectious diseases and avenues to target them
    Stephen-Victor, Emmanuel
    Bosschem, Iris
    Haesebrouck, Freddy
    Bayry, Jagadeesh
    CELLULAR MICROBIOLOGY, 2017, 19 (06)
  • [5] The Yin and Yang of Inflammation
    Blackman, M. A.
    Yates, J. L.
    Spencer, C. M.
    Vomhof-DeKrey, E. E.
    Cooper, A. M.
    Leadbetter, E. A.
    CURRENT MOLECULAR MEDICINE, 2014, 14 (09) : 1238 - 1243
  • [6] The yin and yang of COPD: or balancing repair (yang) and inflammation (yin)
    Soriano, J. B.
    Agusti, A.
    EUROPEAN RESPIRATORY JOURNAL, 2008, 32 (06) : 1426 - 1427
  • [7] The Yin and Yang of Type 1 Regulatory T Cells: From Discovery to Clinical Application
    Sayitoglu, Ece Canan
    Freeborn, Robert Arthur
    Roncarolo, Maria Grazia
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [8] The Yin and Yang of Follicular Helper T Cells
    Awasthi, Amit
    Kuchroo, Vijay K.
    SCIENCE, 2009, 325 (5943) : 953 - 955
  • [9] The Yin and Yang of arterial inflammation
    Mills, R
    Bhatt, DL
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004, 44 (01) : 50 - 52
  • [10] The Yin and Yang of regulatory T cell and therapy progress in autoimmune disease
    Qiao, Yong-chao
    Pan, Yan-hong
    Ling, Wei
    Tian, Fang
    Chen, Yin-ling
    Zhang, Xiao-xi
    Zhao, Hai-lu
    AUTOIMMUNITY REVIEWS, 2017, 16 (10) : 1058 - 1070
12345