Identification of the ataxin-1 interaction network and its impact on spinocerebellar ataxia type 1

[1] Hu YS(2019)Self-assembling vascular endothelial growth factor nanoparticles improve function inspinocerebellar ataxia type 1 Brain 142 312-321

[2] Do J(2018)Astroglia contribute to the pathogenesis of spinocerebellar ataxia Type 1 (SCA1) in a biphasic, stage-of-disease specific manner Glia 66 1972-1987

[3] Edamakanti CR(2018)ATXN1-CIC complex is the primary driver of cerebellar pathology in spinocerebellar ataxia type 1 through a gain-of-function mechanism Neuron 97 1235-1243

[4] Kini AR(1998)Mice lacking ataxin-1 display learning deficits and decreased hippocampal paired-pulse facilitation J Neurosci 18 5508-5516

[5] Martina M(2018)Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells Sci Data 5 1235-1243

[6] Stupp SI(2020)The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways Nat Commun 11 527-536

[7] Kim JH(2017)Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans Nat Genet 49 399-404

[8] Lukowicz A(2014)Structural basis of the phosphorylation dependent complex formation of neurodegenerative disease protein Ataxin-1 and RBM17 Biochem Biophys Res Commun 449 2252-2265

[9] Qu W(2018)Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1 J Clin Invest 128 1864-3351

[10] Johnson A(2017)Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1 Nat Commun 8 3339-644

[1] Hu YS(2019)Self-assembling vascular endothelial growth factor nanoparticles improve function inspinocerebellar ataxia type 1 Brain 142 312-321

[2] Do J(2018)Astroglia contribute to the pathogenesis of spinocerebellar ataxia Type 1 (SCA1) in a biphasic, stage-of-disease specific manner Glia 66 1972-1987

[3] Edamakanti CR(2018)ATXN1-CIC complex is the primary driver of cerebellar pathology in spinocerebellar ataxia type 1 through a gain-of-function mechanism Neuron 97 1235-1243

[4] Kini AR(1998)Mice lacking ataxin-1 display learning deficits and decreased hippocampal paired-pulse facilitation J Neurosci 18 5508-5516

[5] Martina M(2018)Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells Sci Data 5 1235-1243

[6] Stupp SI(2020)The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways Nat Commun 11 527-536

[7] Kim JH(2017)Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans Nat Genet 49 399-404

[8] Lukowicz A(2014)Structural basis of the phosphorylation dependent complex formation of neurodegenerative disease protein Ataxin-1 and RBM17 Biochem Biophys Res Commun 449 2252-2265

[9] Qu W(2018)Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1 J Clin Invest 128 1864-3351

[10] Johnson A(2017)Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1 Nat Commun 8 3339-644