The current role of preoperative and intraoperative autologous blood donation in pediatric open-heart surgery

被引:2
作者
Hiroomi Murayama
Masanobu Meda
Ken Miyahara
Yoshimasa Sakai
Hajime Sakurai
Hiroki Hasegawa
Akemi Kawamura
机构
[1] Social Insurance Chukyo Hospital,Department of Cardiovascular Surgery
关键词
autologous blood donation; blood transfusion; pediatric open-heart surgery;
D O I
10.1007/s11748-003-0079-3
中图分类号
学科分类号
摘要
Objective: We assessed the current role of preoperative and intraoperative autologous blood donation in pediatric open-heart surgery. Methods: Group 1 consisted of 51 patients between 5 and 10 years old who underwent preoperative autologous blood donation. Group 2 consisted of 50 age-matched patients without preoperative donation as controls. Intraoperative donation was conducted in both groups prior to cardiopulmonary bypass. We evaluated perioperative blood cell count, blood loss, and the need for homologous blood products. Results: No serious complications occurred in preoperative or intraoperative donation. Total preoperative donation storage was 17.5±3.4 mL/kg. Intraoperative donation was 21.7 ±6.1 mL/kg in Group 1 and 12.8±4.0 mL/kg in Group 2 (p<0.001). On admission, serum hemoglobin was lower in Group 1 (12.2±1.0 g/dL versus 13.6±1.6 g/dL, p<0.001) but returned postoperatively to the preoperative value. It hovered at a depressed level in Group 2 (12.2±1.4 versus 10.2±1.1 g/dL, p<0.001). The homologous blood requirement was significantly less in Group 1 than in Group 2 (0% versus 10%, p<0.05). Postoperative platelet counts showed similar curves, and blood loss was not statistically significantly different between groups. Conclusion: Preoperative and intraoperative donations are safe and continue to contribute uniquely to blood conservation, providing important options in comprehensive blood conservation programs in current pediatric open-heart surgery.
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页码:91 / 97
页数:6
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