The roles of melatonin and light in the pathophysiology and treatment of circadian rhythm sleep disorders

被引：0
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作者：
Seithikurippu R Pandi-Perumal
Ilya Trakht
D Warren Spence
Venkataramanujan Srinivasan
Yaron Dagan
Daniel P Cardinali
机构：
[1] College of Physicians and Surgeons at Columbia University,SR Pandi
[2] New York,Perumal is the President and Chief Executive Officer of Somnogen Inc. and I Trakht is an Assistant Professor in the Division of Clinical Pharmacology and Experimental Therapeutics, Department of Medicine
[3] NY,V Srinivasan is an Associate Professor in the Department of Physiology
[4] USA.,Y Dagan is a Senior Emergency Physician and Head of the Medical Education Department in the Faculty of Medicine at Tel Aviv University
[5] DW Spence is a PhD student at the University of Toronto,undefined
[6] Toronto,undefined
[7] ON,undefined
[8] Canada.,undefined
[9] School of Medical Sciences at University Sains Malaysia,undefined
[10] Kota Bharu,undefined
[11] Kelantan,undefined
[12] Malaysia.,undefined
[13] Tel Aviv,undefined
[14] Israel.,undefined
[15] DP Cardinali is Professor of Physiology and Director of the Neuroscience Laboratory in the Faculty of Medicine at University of Buenos Aires,undefined
[16] Buenos Aires,undefined
[17] Argentina.,undefined
来源：
Nature Clinical Practice Neurology | 2008年 / 4卷
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摘要：
Desynchronization of circadian rhythms is a common occurrence in individuals presenting with sleep disorders. In this Review, Pandi-Perumal et al. highlight the roles of light and endogenous melatonin in the synchronization of sleep–wake rhythms and rest–activity cycles with the light–dark cycle, and they discuss how light therapy and exogenous melatonin might be used to treat circadian rhythm sleep disorders.
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页码：436 / 447
页数：11
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