Functional magnetic resonance imaging (fMRI) of the sensorimotor cortex in spinal cord injury patient after intensive rehabilitation

被引：1
作者：
Lima F.P.S. [1 ]
Lima M.O. [1 ]
Álvarez N.L. [2 ]
Lopes-Martins R.Á.B. [3 ]
Lucareli P.R.G. [4 ]
Bargalló N. [5 ]
Falcon C. [6 ]
Vidal J. [7 ]
Junqué C. [8 ]
机构：
[1] Laboratory of Sensory Motor Rehabilitation, Instituto de Pesquisa & Desenvolvimento-IP&D, Universidade do Vale do Paraíba-UNIVAP, Av. Shishima Hifumi, 2911 – Urbanova, São José dos Campos, 12244-000, SP
[2] Advanced Neurorehabilitation Unit, Hospital Los Madroños, Madrid
[3] Laboratory of Biophotonics and Experimental Therapeutics, Instituto de Pesquisa & Desenvolvimento-IP&D, Universidade do Vale do Paraíba-UNIVAP, São José dos Campos, SP
[4] Laboratory of Analysis of Human Movement - Nucleus of Research Support in Analysis of the Movement, Universidade Nove de Julho (UNINOVE), São Paulo, SP
[5] August Pi and Sunyer Biomedical Research Institute – IDIBAPS, Hospital Clinic of Barcelona, Barcelona
[6] Barcelonaβeta Brain Research Center, Fundación Pasqual Maragall, Barcelona
[7] Institute Guttmann Hospital of Neurorehabilitation, Badalona, Barcelona
[8] Department of Psychiatry and Clinical Psychobiology, Universitat de Barcelona, Barcelona
来源：
Lima, Fernanda Pupio Silva (fpupiolima@gmail.com) | 1600年 / Springer Science and Business Media Deutschland GmbH卷 / 36期
关键词：
fMRI; Motor rehabilitation; Robotics; Sensorimotor reorganization; Spinal cord injury;
D O I：
10.1007/s42600-020-00056-w
中图分类号：
学科分类号：
摘要：
Purpose: The sensorimotor cortex may play a role in the functional recovery after a spinal cord injury (SCI) through efference generated in the absence of the afference. The purpose of this study was to evaluate the potential reorganization in the sensorimotor cortex in SCI patients after body weight supported treadmill training (BWSTT) associated with conventional motor rehabilitation. Methods: Seven SCI patients with American Spinal Injury Association Impairment Scale (AIS) C and D participated in this study. SCI patients were submitted to a motor task functional magnetic resonance imaging study (fMRI) before and after the rehabilitation treatment. Results: All patients showed significant changes in the brain activation following motor rehabilitation. After treatment, a decrease in the activation of the cerebellum and an increase of basal ganglia activation were observed. Conclusion: The results suggest that the cerebellum is less recruited when acquiring an automatic movement, and the basal ganglia contribute to the cortical reorganization process to promote a functional motor recovery. © 2020, Sociedade Brasileira de Engenharia Biomedica.
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页码：129 / 137
页数：8
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