A hypoperfusion context may aid to interpret hyperlactatemia in sepsis-3 septic shock patients: a proof-of-concept study

[1] Singer M(2016)The third international consensus definitions for sepsis and septic shock (Sepsis-3) JAMA 315 801-810

[2] Deutschman CS(2013)Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012 Crit Care Med 41 580-637

[3] Seymour CW(2014)Sepsis-associated hyperlactatemia Crit Care 18 503-286

[4] Shankar-Hari M(2012)The holistic view on perfusion monitoring in septic shock Curr Opinion Crit Care 18 280-1815

[5] Annane D(2015)Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion Crit Care 19 188-761

[6] Bauer M(2014)Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine Intensive Care Med 40 1795-805

[7] Dellinger RP(2010)Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial Am J Respir Crit Care Med 182 752-480

[8] Levy MM(2015)Combination of arterial lactate levels and venous-arterial CO Intensive Care Med 41 796-1377

[9] Rhodes A(2014) to arterial-venous O Ann Intensive Care 4 30-2225

[10] Annane D(2015) content difference ratio as markers of resuscitation in patients with septic shock Am J Respir Crit Care Med 191 477-288

[1] Singer M(2016)The third international consensus definitions for sepsis and septic shock (Sepsis-3) JAMA 315 801-810

[2] Deutschman CS(2013)Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012 Crit Care Med 41 580-637

[3] Seymour CW(2014)Sepsis-associated hyperlactatemia Crit Care 18 503-286

[4] Shankar-Hari M(2012)The holistic view on perfusion monitoring in septic shock Curr Opinion Crit Care 18 280-1815

[5] Annane D(2015)Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion Crit Care 19 188-761

[6] Bauer M(2014)Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine Intensive Care Med 40 1795-805

[7] Dellinger RP(2010)Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial Am J Respir Crit Care Med 182 752-480

[8] Levy MM(2015)Combination of arterial lactate levels and venous-arterial CO Intensive Care Med 41 796-1377

[9] Rhodes A(2014) to arterial-venous O Ann Intensive Care 4 30-2225

[10] Annane D(2015) content difference ratio as markers of resuscitation in patients with septic shock Am J Respir Crit Care Med 191 477-288