Asymmetry of modifications of the electrical activity of the rat cortex induced by intraventricular injections of thyrotropin-releasing hormone

被引：0
作者：
B. A. Lobasyuk
S. A. Andronati
S. V. Kostenko
A. A. Mazurov
L. S. Godlevskii
机构：
[1] Mechnikov Odessa National University,Bogatskii Physico
[2] National Academy of Sciences of Ukraine,Chemical Institute
[3] Ministry of Public Health of Ukraine,Odessa State Medical University
来源：
Neurophysiology | 2004年 / 36卷
关键词：
thyrotropin-releasing hormone; antidepressive effects; electrocorticogram; functional interhemisphere asymmetry;
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学科分类号：
摘要：
We studied modifications in the mass electrical activity of the cortex (ECoG) induced by injections of thyrotropin-releasing hormone (TRH) into the left or right lateral brain ventricle in rats kept under conditions close to free behavior. It was found that these effects are characterized by a significant interhemisphere asymmetry. We postulate that the pharmacological (in particular, antidepressive) effects of TRH are related to its ability to intensify inhibitory processes in the left cerebral hemisphere and activating processes in the right hemisphere.
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页码：340 / 346
页数：6
相关论文
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