Assessment of saccular function using cervical vestibular-evoked myogenic potentials in children with sensorineural hearing loss

被引：2
作者：
Selim M.H. [1 ]
El-Abd S.M. [1 ]
El-Minawi M.S. [1 ]
Nassef A.A.F. [2 ]
Yousef B.M. [3 ]
机构：
[1] Audiology Unit, ENT Department, Kasr El-Aini Hospital, Cairo University, P.O. Box 11121, Cairo
[2] Department of Radiology, Kasr El-Aini Hospital, Cairo University, Cairo
[3] Ministry of Health, Tanta
来源：
The Egyptian Journal of Otolaryngology | 2012年 / 28卷 / 3期
关键词：
cochlea; pure tone audiometry; saccule; sensorineural hearing loss; sternocleidomastoid muscle; vestibular-evoked myogenic potentials;
D O I：
10.7123/01.EJO.0000418053.78780.0c
中图分类号：
学科分类号：
摘要：
Abstract Objectives: The aim of this work was to examine saccular function using cervical vestibular-evoked myogenic potentials (cVEMPs) in children with congenital or acquired sensorineural hearing loss (SNHL). Study design: Descriptive cross-sectional study. Participants and methods: This study was carried out on 30 children with different degrees of SNHL with normal middle ear function and 25 age-matched and sex-matched typically developing children. All the participants’ age ranged from 5 to 18 years. For each child, the following were administered: history taking, an otologic examination, a basic audiological evaluation in the form of pure tone audiometry and immittancemetry, air-conducted cVEMPs, and computed tomography scan of the temporal bone. The results obtained from the two groups were then compared. In addition, correlation studies between all the results obtained were carried out. Results: There was a statistically nonsignificant difference between the patients and the controls in cVEMP P13 and N23 latencies, whereas the cVEMP P13–N23 amplitude and threshold results showed a highly significant difference. cVEMP measurements in relation to sex within the patient group showed that the cVEMP threshold was the only positive outcome that showed a significant difference, and was higher in females. There was a highly significant positive correlation between hearing loss and the cVEMP threshold among the patient groups with different degrees of hearing losses. In addition, there was a significant positive correlation between age and cVEMP P13 and N23 latencies among the patient group. Conclusion: SNHL is associated with saccular dysfunction in the pediatric population in the form of decreased cVEMP P13–N23 amplitudes and elevated cVEMP thresholds. Females presented with higher cVEMP threshold values than men, and cVEMP latencies appear to increase with age. An increase in hearing loss is associated with an increase in the cVEMP threshold and cVEMP amplitude appears to decrease with hearing loss irrespective of its degree. We recommend the inclusion of cVEMPs in the battery of evaluation of children with SNHL to detect early subtle changes in saccular function. Future research focusing on the genes causing SNHL and its relation to VEMP findings should be carried out. © 2012, The Egyptian Oto - Rhino - Laryngological Society.
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页码：234 / 241
页数：7
相关论文
共 34 条
[1]  
Mueller R.F., Nehammer A., Middleton A., Houseman M., Taylor G.R., Bitner-Glindzciz M., Et al., Congenital non-syndromal sensorineural hearing impairment due to connexin 26 gene mutations–molecular and audiological findings, Int J Pediatr Otorhinolaryngol, 50, pp. 3-13, (1999)
[2]  
Kim L.S., Jeong S.W., Lee Y.M., Cochlear implantation in children, Auris Nasus Larynx., 37, pp. 6-17, (2010)
[3]  
Suarez H., Angeli S., Suarez A., Rosales B., Carrera X., Alonso R., Balance sensory organization in children with profound hearing loss and cochlear implants, Int J Pediatr Otorhinolaryngol., 71, pp. 629-637, (2007)
[4]  
An M.-H., Yi C.-H., Jeon H.-S., Park S.-Y., Age-related changes of single-limb standing balance in children with and without deafness, Int J Pediatr Otorhinolaryngol., 73, pp. 1539-1544, (2009)
[5]  
Zhou G., Kenna M.A., Stevens K., Licameli G., Assessment of saccular function in children with sensorineural hearing loss, Arch Otolaryngol Head Neck Surg., 135, pp. 40-44, (2009)
[6]  
Rosengren S.M., Todd N.P.M., Colebatch J.G., Vestibular evoked myogenic potentials evoked by brief interaural head acceleration: properties and possible origin, J Appl Physiol., 107, pp. 841-852, (2009)
[7]  
Picciotti P.M., Fiorita A., Di Nardo W., Calo L., Scarano E., Paludetti G., Vestibular evoked myogenic potentials in children, Int J Pediatr Otorhinolaryngol., 71, pp. 29-33, (2007)
[8]  
Zagolski O., Vestibular-evoked myogenic potentials and caloric stimulation in infants with congenital cytomegalovirus infection, J Laryngol Otol., 122, pp. 574-579, (2008)
[9]  
Erbek S., Erbek S.S., Gokmen Z., Ozkiraz S., Tarcan A., Ozluoglu L.N., Clinical application of vestibular evoked myogenic potentials in healthy newborns, Int J Pediatr Otorhinolaryngol., 71, pp. 1181-1185, (2007)
[10]  
Brantberg K., Vestibular evoked myogenic potentials (VEMPs): usefulness in clinical neurotology, Semin Neurol., 29, pp. 541-547, (2009)
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