Cytosine base editors go off-target

被引：0
作者：
Katharine H. Wrighton
机构：
[1] Nature Reviews Genetics,
来源：
Nature Reviews Genetics | 2019年 / 20卷
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摘要：
Two studies in Science show that cytosine base editors, but not adenine base editors or CRISPR–Cas9, induce notable off-target single-nucleotide variants in rice and in mouse embryos.
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页码：254 / 255
页数：1
相关论文
共 4 条
[1]  
Jin S(2019)Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice Science 19 770-788
[2]  
Zuo E(2019)Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos Science undefined undefined-undefined
[3]  
Rees HA(2018)Base editing: precision chemistry on the genome and transcriptome of living cells Nat. Rev. Genet. undefined undefined-undefined
[4]  
Liu DR(undefined)undefined undefined undefined undefined-undefined
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